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Walled-off pancreatic necrosis (WON) is a defined entity that occurs following an episode of acute necrotizing pancreatitis. Direct endoscopic necrosectomy (DEN) is performed by advancing an endoscope transmurally into WON and has become an accepted modality. However, clinicians have many questions about endoscopic necrosectomy. Some of these questions will be addressed. 1. Is DEN required […]

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Over the years there have been attempts at standardizing care for the patient with inflammatory bowel disease (IBD). I was the director of AGA’s initiative to establish quality metrics for the care of patients with IBD in 2011. Subramanian and Triadafilopoulos published a review in 2016,1 and Berry and Melmed published an excellent review this […]


This is half of a two-part debate — read the opposing argument.  Following the introduction of infliximab in 1998, two additional tumor necrosis factor antagonists (i.e., adalimumab, certolizumab pegol), the anti- integrin vedolizumab and ustekinumab (a monoclonal directed to interleukin 12 and 23) were approved for the management of inflammatory bowel disease. Biologics have greatly […]


The inaugural Crohn’s & Colitis Congress™ (Jan. 18-20, 2018, Las Vegas, Nevada) gathered more than 1,250 inflammatory bowel disease (IBD) health care professionals and featured more than 250 abstracts — with the goal of advancing research and transforming the care of IBD patients. The Crohn’s & Colitis Congress is a new partnership between the Crohn’s […]