Debates

Celiac disease is diagnosed by small intestinal biopsy. As the popularity of the gluten-free diet has surged in the past decade, histology has largely remained intact as the arbiter between celiac disease and non-celiac gluten sensitivity, a condition whose etiology, pathogenesis and natural history remain incompletely understood. Though a pathway for a biopsy-free diagnosis of […]

Debates

Broadly, my celiac patients suffer from two main problems. The first is poorly controlled celiac disease, with some combination of ongoing symptoms, enteropathy and laboratory abnormalities. This group, collectively referred to as nonresponsive celiac disease, is significant and although all current data on this issue comes from a few tertiary referral centers, it is likely […]

Quick Hits

IBS is the most common intestinal disorder in our society, and is characterized by abdominal pain and altered bowel habit in the absence of an underlying structural abnormality. IBS is often diagnosed by the costly exclusion of other diseases, which may include celiac diseaseā€ a chronic enteropathy triggered by gluten in persons with genetic predisposition. […]