Debates

Barrett’s esophagus is a metaplastic change of the esophageal epithelium which increases the risk of esophageal adenocarcinoma by 10 to 30 fold. It is thought to progress via the development of dysplasia to esophageal adenocarcinoma (EAC). EAC is a lethal malignancy with poor outcomes when diagnosed after the onset of symptoms despite recommendations for screening […]

Debates

Aspirin is a commonly prescribed drug and its prevention of both cardiovascular and vascular events is well established. Recently, the benefits of aspirin from a chemoprevention standpoint, particularly in gastrointestinal tract cancers, have emerged. Prevention of esophageal adenocarcinomas is particularly relevant for Barrett’s esophagus patients, a premalignant condition affecting 2 percent of the adult population. […]