Quick Hits

Some of my most painful clinical encounters have been with young persons with advanced colorectal cancer (CRC) in whom opportunities for early diagnosis or prevention were missed: the young woman with obstructing CRC in late pregnancy after 14 months of symptoms that were not evaluated because of lack of insurance and then reluctance to perform […]

Quick Hits

This commentary describes the current status of the multi-target stool DNA test (mt-sDNA) (Cologuard®, Exact Sciences, Madison, WI) and of stool-based markers for GI diseases. Approved by both the U.S. Food and Drug Administration and the Center for Medicare and Medicaid Services in August 2014, the mt-sDNA test is a non-invasive screening test for colorectal […]

Quick Hits

The link between chronic inflammatory bowel disease (IBD) and colon cancer is well established. Colorectal cancer (CRC) is increased in patients with IBD involving at least one-third of the colon, and it is important to remember that it is the same for Crohn’s disease and ulcerative colitis. Classically, the risk of CRC was estimated to […]

Debates

As a card-carrying gastroenterologist, I enjoy performing screening colonoscopy just like most of my society brethren. However, I feel strongly that the fecal immunochemical test (FIT) is a fully acceptable alternative for colorectal cancer (CRC) screening. Perhaps the easiest defense for those of us who are enthusiastic about stool-based screening is the quality of evidence supporting it. […]

Debates

In Australia and some European countries, colorectal cancer (CRC) screening occurs in an organized or programmatic setting, usually funded by the national government. Organized screening commonly relies on fecal occult blood testing (FOBT) as the primary means of screening, and usually the fecal immunochemical test (FIT). FIT is a good option for these programs as […]

Debates

In his 2015 State of the Union Address, President Obama launched the era of precision medicine, which proposes medical decisions and practices tailored to the individual patient. While the concept of precision medicine is not new, what is new is the broader scope in which precision medicine will eventually apply. Broader application of precision medicine […]