The opinion magazine of the American Gastroenterological Association
This is half of a two-part debate — read the opposing argument. Esophageal symptoms are common and affect at least a quarter of the population. There are a multitude of diagnostic tests available, but no true gold standard and each test is complementary. Endoscopy allows direct visualization of the mucosa, biopsy acquisition and potential dilation […]
This is half of a two-part debate — read the opposing argument. Preamble to this article: I did not volunteer to write this opinion paper, but was asked by the outgoing editor, Dr. Gary Falk. Why, I’m not sure, because I don’t have this technology in our Esophageal Center at the University of South Florida. […]
AGA’s 2018 Presidential Plenary session was packed, and excitement in the room was palpable! On the stage sat Sheila Crowe, our outgoing president, with David Lieberman, our incoming president. Our new logo was proudly and prominently displayed. In addition to expert presentations on eosinophilic esophagitis, colon cancer and inflammatory bowel disease, several abstracts were highlighted. […]
A meaningful discussion on the relevance of proton pump inhibitor–responsive esophageal eosinophilia (PPI-REE) in 2018 should first consider this question: How did we ever end up with this cumbersome term? Well, it arose as an artifact of early confusion regarding the need to distinguish eosinophilic esophagitis (EoE) from gastroesophageal reflux disease (GERD). This confusion led […]
Making the diagnosis of eosinophilic esophagitis (EoE), a clinicopathologic disease, requires the integration of patient symptoms, histology and clinical data. As gastroenterologists, we are obliged to do the same when monitoring for a therapeutic response. Although there are several axes on which EoE treatments may be assessed, no single measure has been shown to be sufficient. Therefore, considering the subjective experience together […]
When we think about the optimal approach to managing patients with eosinophilic esophagitis (EoE), an important question arises: what is the most meaningful endpoint for therapy in EoE — is it histologic remission, endoscopic improvement or symptomatic resolution? While there may be some controversy among investigators regarding which endpoint is most important, most will agree […]
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