Quick Hits

This commentary describes the current status of the multi-target stool DNA test (mt-sDNA) (Cologuard®, Exact Sciences, Madison, WI) and of stool-based markers for GI diseases. Approved by both the U.S. Food and Drug Administration and the Center for Medicare and Medicaid Services in August 2014, the mt-sDNA test is a non-invasive screening test for colorectal […]


As a card-carrying gastroenterologist, I enjoy performing screening colonoscopy just like most of my society brethren. However, I feel strongly that the fecal immunochemical test (FIT) is a fully acceptable alternative for colorectal cancer (CRC) screening. Perhaps the easiest defense for those of us who are enthusiastic about stool-based screening is the quality of evidence supporting it. […]