The opinion magazine of the American Gastroenterological Association
AGA Research Foundation pilot research awards are an invaluable tool for investigators. They provide seed funding to explore promising new lines of research and generate preliminary data for larger grants. When Ans Pauwels, PhD, MPharmSc, received the 2016 AGA-Rome Foundation Pilot Award in Functional Gastrointestinal and Motility Disorders from the AGA Research Foundation, she was able to intensify her […]
Endoscopic eradication therapy (EET) with a combined approach of resection and ablation is safe and effective. The evolution of endoscopic mucosal resection (EMR) for visible lesions followed by radiofrequency ablation (RFA) has become the gold standard for Barrett’s associated neoplasia. Despite the effectiveness of EET, recurrence of intestinal metaplasia (IM) after achieving complete eradication (CE-IM) […]
Esophageal adenocarcinoma (EAC) has been the most rapidly increasing solid cancer in the U. S. during the past three decades. The prognosis of this cancer remains dismal with only one in five patients overall and three in five patients with localized cancer surviving over five years. Our only hope in this disease is to prevent […]
This is half of a two-part debate — read the opposing argument. For most individuals with gastroesophageal reflux, treatment with antisecretory medication yields excellent symptom relief. However, medical management fails in a subset of patients with more severe symptoms, and antireflux surgery should be considered. Traditionally the procedure of choice has been a 360° (Nissen) […]
This is half of a two-part debate — read the opposing argument. Gastroesophageal reflux disease (GERD) is one of the most common disorders in the U.S., affecting more than 25 million people. Despite the high prevalence of this disease, not much progress has been made in treating it in the last 30 to 70 years. Einstein […]
The first clinical descriptions of eosinophilic esophagitis (EoE) emerged over two decades ago. Subsequently, adults with food impaction or dysphagia or change to children with non-descriptive gastroesophageal reflux disease (GERD)–like symptoms are increasingly recognized as having something different than GERD. Soon thereafter, a whole set of distinct eosinophilic GI diseases (EGID) involving various segments of […]
We are all aware that the incidence of esophageal adenocarcinoma has been rising rapidly over the last 50 years. Since the cancer is associated with an endoscopically visible lesion in Barrett’s esophagus, screening for esophageal adenocarcinoma ought to be relatively easy compared to screening for other terrible cancers, such as pancreatic or ovarian. But there […]
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