Debates

This is half of a two-part debate — read the opposing argument. Innovation requires rigorous vetting for successful and sustained implementation. Such is the case for liver transplantation for alcoholic hepatitis. The seminal paper by Mathurin et al in 2011 stimulated debate regarding liver transplantation for patients with acute alcoholic hepatitis.1 This study showed that […]

Quick Hits

The gut-brain axis is a relatively new focus of research that has rapidly expanded after the development of culture-independent analytic techniques. Of interest to hepatologists is the microbiome-gut-liver- brain axis and its role in the pathogenesis of hepatic encephalopathy (HE). HE is defined as brain dysfunction secondary to liver insufficiency and/or portosystemic shunts, which is […]

Quick Hits

Cirrhosis is the most common cause of portal hypertension and varices in the Western world. However, varices can arise in patients with portal hypertension in the absence of cirrhosis or even in the absence of portal hypertension. This short perspective focuses on varices without cirrhosis, including background information and various diagnosis and treatment options. Non-Cirrhotic […]