The opinion magazine of the American Gastroenterological Association
In the absence of robust prospective data, the conversation about pancreatic cysts has mostly been driven by low-quality evidence, expert consensus and opinion. Hence, when debating an issue such as the role of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic cysts greater than 3 cm, one can, within reason, construct an argument to support either […]
Pancreatic cystic lesions are widely identified now because of the increased use and improved resolution of cross-sectional imaging. The majority of these cysts are found in older patients, often when imaging is performed for an unrelated condition such as our patient with a suspected kidney stone. This leads to tremendous anxiety for the patient and […]
Obesity is a worsening pandemic that afflicts more than 35 percent of the U.S. adult population and hundreds of millions of people on a global scale. This dwarfs other common medical conditions, such as colon cancer, esophageal cancer, cirrhosis, HIV and IBD, and is several fold more prevalent than all of these combined. Obesity is […]
Change. An old adage stipulates it is the one true constant in life, or, stated another way, “Change is inevitableexcept from a vending machine” (Robert Gallagher). On behalf of our new Board of Editors, we are honored, humbled and excited to oversee the next editorship team for Gastroenterology. The next iteration of Gastroenterology’s Board of […]
The increased digitization and subsequent dissemination of large volumes of electronic medical records, research and development information, billing data, and biometrics have created unprecedented opportunities to improve outcomes, reduce costs and accelerate innovation in health care. Colloquially referred to as “big data,” these enormous datasets are often both structured and unstructured, and difficult to analyze […]
Vedolizumab (Entyvio, Takeda Pharmaceuticals America, Deerfield, IL) is a humanized monoclonal antibody to α-4 β-7 integrin, which is expressed on lymphocytes and is the ligand to mucosal vascular addressin cell adhesion molecule-1 (MAdCAM-1), preferentially expressed on endothelial cells in the gut vasculature. Vedolizumab selectively interferes with lymphocyte homing in the gut, thus affording the potential […]
The first clinical descriptions of eosinophilic esophagitis (EoE) emerged over two decades ago. Subsequently, adults with food impaction or dysphagia or change to children with non-descriptive gastroesophageal reflux disease (GERD)–like symptoms are increasingly recognized as having something different than GERD. Soon thereafter, a whole set of distinct eosinophilic GI diseases (EGID) involving various segments of […]
The advances in treatment of chronic hepatitis C virus (HCV) infection over the past five years have been nothing short of historic in scope and impact. Since 2011, a total of 12 oral direct acting antiviral agents (DAAs) have been approved by the U.S. Food and Drug Administration across four classes of drugs, including NS3/4A […]
In the absence of robust prospective data, the conversation about pancreatic cysts has mostly been driven by low-quality evidence, expert consensus and opinion. Hence, when debating an issue such as the role of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic cysts greater than 3 cm, one can, within reason, construct an argument to support either […]
Pancreatic cystic lesions are widely identified now because of the increased use and improved resolution of cross-sectional imaging. The majority of these cysts are found in older patients, often when imaging is performed for an unrelated condition such as our patient with a suspected kidney stone. This leads to tremendous anxiety for the patient and […]
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