Quick Hits

Despite nearly 15 years of clinical availability, computed tomography colonography (CTC) remains an infrequently utilized method of colorectal cancer (CRC) screening. High-quality trials and meta-analyses demonstrate comparable test performance between CTC and colonoscopy to detect colorectal polyps in average-risk individuals, especially for polyps 1 cm or greater. Variation in insurance coverage, limited endorsement by gastroenterology […]

Quick Hits

It is both an exciting and challenging time for diagnostic endoscopy. The latest endoscopy platforms provide sharp, high-resolution images of the gastrointestinal tract that help us distinguish subtle mucosal and vascular patterns. By itself, this represents a significant improvement in performance compared to standard-definition endoscopy. In parallel, several advanced imaging modalities have emerged that provide […]

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Ever find yourself getting off your highway exit, not remembering most of the trip?  Chances are you were in a hypnotic trance — a state of intense mental focus, reduced awareness of the environment around you and a heightened ability to receive suggestions that would normally seem unbelievable. Luckily, without the occurrence of the latter, […]

Debates

This is half of a two-part debate — read the opposing argument. For most individuals with gastroesophageal reflux, treatment with antisecretory medication yields excellent symptom relief. However, medical management fails in a subset of patients with more severe symptoms, and antireflux surgery should be considered. Traditionally the procedure of choice has been a 360° (Nissen) […]

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Worldwide, idiosyncratic drug-induced liver injury (DILI) is an uncommon but important cause of acute and chronic liver disease. In general, the susceptibility of DILI is not related to the dose or duration of suspect medication use but rather has been attributed to novel host factors that may involve the individual patients’ microbiome, genome, or transcriptome.1 […]