Quick Hits

The gut-brain axis is a relatively new focus of research that has rapidly expanded after the development of culture-independent analytic techniques. Of interest to hepatologists is the microbiome-gut-liver- brain axis and its role in the pathogenesis of hepatic encephalopathy (HE). HE is defined as brain dysfunction secondary to liver insufficiency and/or portosystemic shunts, which is […]

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The first esophageal peroral endoscopic myotomy (POEM) series was reported in 2010 by Professor Harohiro Inoue. Seven years later, more than 7,000 procedures have been performed worldwide culminating in a recent AGA Clinical Practice Update stating, “if the expertise is available, POEM should be considered as a treatment option comparable with laparoscopic Heller myotomy for […]

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Epidemiology. Recent data from the U.S. Cancer Statistics registry show that hepatocellular carcinoma (HCC) continues to rise albeit at a slower rate recently (4.5 percent increase annually from 2000 to 2009, and 0.7 percent from 2010 to 2012). Men between 55 and 64 years of age, Hispanics and, at state-level, Texans, are the most commonly […]

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Some of my most painful clinical encounters have been with young persons with advanced colorectal cancer (CRC) in whom opportunities for early diagnosis or prevention were missed: the young woman with obstructing CRC in late pregnancy after 14 months of symptoms that were not evaluated because of lack of insurance and then reluctance to perform […]